El gengibre previene la diabetes

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El gengibre previene la diabetes

Notapor Fisio » Sab, 08 Feb 2014, 19:42

El gengibre previene la diabetes, o al menos mejora los marcadores asociados

Ginger reduced [b]fasting plasma glucose
, HbA1C, insulin, HOMA, triglyceride, total cholesterol, CRP and PGE2 significantly compared with placebo group (p < 0.05)[/b]

Int J Food Sci Nutr. 2014 Feb 4.
The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus.

Abstract Objective: To assess the effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Methods: In a double-blinded, placebo-controlled clinical trial, 70 type 2 diabetic patients were enrolled. They allocated randomly into ginger group and control group. They consumed 1600 mg ginger versus 1600 mg wheat flour placebo daily for 12 weeks. Serum sugar, lipids, CRP, PGE2 and TNFα were measured before and after intervention. Results: Ginger reduced fasting plasma glucose, HbA1C, insulin, HOMA, triglyceride, total cholesterol, CRP and PGE2 significantly compared with placebo group (p < 0.05). There were no significant differences in HDL, LDL and TNFα between two groups (p > 0.05). Conclusion: Ginger improved insulin sensitivity and some fractions of lipid profile, and reduced CRP and PGE2 in type 2 diabetic patients. Therefore ginger can be considered as an effective treatment for prevention of diabetes complications.


http://www.ncbi.nlm.nih.gov/pubmed/24490949
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Re: El gengibre previene la diabetes

Notapor Fisio » Sab, 08 Feb 2014, 19:44

Int J Food Sci Nutr. 2013 Sep;64(6):682-6. doi: 10.3109/09637486.2013.775223.
Effects of ginger (Zingiber officinale) on plasma glucose level, HbA1c and insulin sensitivity in type 2 diabetic patients.


The present study was aimed to evaluate the effects of Zingiber officinale on some biochemical parameters in type 2 diabetic (DM2) patients. In a randomized double-blind placebo controlled trial, 64 patients with DM2 were assigned to ginger or placebo groups (receiving 2 g/d of each). A 3 d diet record, anthropometric measurements and concentrations of fasting blood glucose (FPG), HbA1c, lipid profile (including total cholesterol, triglyceride, low density lipoprotein and high density lipoprotein) and also the homeostasis model assessment (HOMA) and quantitative insulin-sensitivity check index (QUICKI) were determined before and after 2 months of intervention. Ginger supplementation significantly lowered the levels of insulin (11.0 ± 2.3 versus 12.1 ± 3.3; p = 0.001), LDL-C (67.8 ± 27.2 versus 89.2 ± 24.9; p = 0.04), TG (127.7 ± 43.7 versus 128.2 ± 37.7; p = 0.03) and the HOMA index (3.9 ± 1.09 versus 4.5 ± 1.8; p = 0.002) and increased the QUICKI index (0.313 ± 0.012 versus 0.308 ± 0.012; p = 0.005) in comparison to the control group; while, there were no significant changes in FPG, TC, HDL-C and HbA1c (p > 0.05). In summary, ginger supplementation improved insulin sensitivity and some fractions of lipid profile in DM2 patients. Therefore it may be considered as a useful remedy to reduce the secondary complications of DM2.


http://www.ncbi.nlm.nih.gov/pubmed/23496212
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Re: El gengibre previene la diabetes

Notapor Fisio » Jue, 13 Nov 2014, 02:23

The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
Mozaffari-Khosravi H1, Talaei B2, Jalali BA3, Najarzadeh A2, Mozayan MR4.
Author information

1Department of Nutrition, Faculty of Health, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: mozaffari.kh@gmail.com.
2Department of Nutrition, Faculty of Health, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3Department of Biochemistry, Faculty of Medical Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4Department of English Language, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Abstract
OBJECTIVE:

To identify the effect of some herbal products on insulin resistance. Regarding the scientific evidences existing about ginger, this research was therefore carried out to identify the effect of ginger supplementation on insulin resistance and glycemic indices in diabetes mellitus.
METHODS:

This is a randomized, double-blind, placebo-controlled trial in which 88 participants affected by diabetes were randomly assigned into ginger (GG) and placebo (PG) groups. The GG received 3 one-gram capsules containing ginger powder whereas the PG received 3 one-gram microcrystalline-containing capsules daily for 8 weeks. HbA1c, fructosamine, fasting blood sugar (FBS), fasting insulin, homeostasis model assessment insulin resistance index (HOMA-IR), β-cell function (β%), insulin sensitivity (S%) and the quantitative insulin sensitivity check index (QUICKI) were assessed before and after the intervention.
RESULTS:

FBS mean showed a decrease of 10.5% (p=0.003) in the GG whereas the mean had an increase of 21% in the PG (p=0.01). Variation in HbA1c mean was in line with that of FBS. Statistical difference was found in the two groups before and after the intervention in terms of median of fasting insulin level, S% and HOMA-IR (P<0.005). Moreover QUICKI mean increased significantly in the two groups, the mean difference, however, was significantly higher in the GG.
CONCLUSIONS:

The study demonstrated that daily consumption of 3 one-gram capsules of ginger powder for 8 weeks is useful for patients with type 2 diabetes due to FBS and HbA1c reduction and improvement of insulin resistance indices such as QUICKI index.


http://www.ncbi.nlm.nih.gov/pubmed/24559810
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