Los niveles de bisfenol A en orina relacionados con el sobrepeso

Foro general ciencia, medicina, nutrición, salud pública, política

Moderador: Fisio

Los niveles de bisfenol A en orina relacionados con el sobrepeso

Notapor Fisio » Mié, 02 Abr 2014, 01:13

Urine Bisphenol-A Level in Relation to Obesity and Overweight in School-Age Children

Bisphenol-A (BPA) is a potential endocrine disruptor impacting metabolic processes and increasing the risk of obesity. To determine whether urine BPA level is associated with overweight/obesity in school-age children, we examined 1,326 students in grades 4–12 from three schools (one elementary, one middle, and one high school) in Shanghai. More than 98% of eligible students participated. Total urine BPA concentration was measured and anthropometric measures were taken by trained research staff. Information on risk factors for childhood obesity was collected for potential confounders. Age- and gender-specific weight greater than 90th percentile of the underlying population was the outcome measure. After adjustment for potential confounders, a higher urine BPA level (≥2 µg/L), at the level corresponding to the median urine BPA level in the U.S. population, was associated with more than two-fold increased risk of having weight >90th percentile among girls aged 9–12 (adjusted odds ratio (aOR) = 2.32, 95% confidence interval: 1.15–4.65). The association showed a dose-response relationship with increasing urine BPA level associated with further increased risk of overweight (p = 0.006 for trend test). Other anthropometric measures of obesity showed similar results. The same association was not observed among boys. This gender difference of BPA effect was consistent with findings from experimental studies and previous epidemiological studies. Our study suggests that BPA could be a potential new environmental obesogen. Widespread exposure to BPA in the human population may also be contributing to the worldwide obesity epidemic.


http://www.plosone.org/article/info%3Ad ... ne.0065399
Avatar de Usuario
Fisio
Administrador del Sitio
 
Mensajes: 6242
Registrado: Dom, 01 Sep 2013, 14:18

Re: Los niveles de bisfenol A en orina relacionados con el sobrepeso

Notapor Valanor » Mié, 02 Abr 2014, 09:10

A estas alturas, creo que seria hasta sano tomarse un IA diaramente para estar "normal".
Por que algo natural para los estrogenos, no hay nada decente no? Almenos yo no he encontrado nada.
Código de descuento iHerb: JGJ833
Código de descuento Myprotein: MP27139542
Código de descuento Powdercity: http://powdercity.refr.cc/46RWDWL
Avatar de Usuario
Valanor
 
Mensajes: 216
Registrado: Mié, 25 Sep 2013, 19:39
Ubicación: Barcelona

Re: Los niveles de bisfenol A en orina relacionados con el sobrepeso

Notapor Fisio » Mié, 02 Abr 2014, 23:40

Valanor escribió:A estas alturas, creo que seria hasta sano tomarse un IA diaramente para estar "normal".
Por que algo natural para los estrogenos, no hay nada decente no? Almenos yo no he encontrado nada.


Si que hay, pero habría que tomar un coctel de varias cosas. Por ejemplo la cúrcuma misma

Curcumin inhibits endometriosis endometrial cells by reducing estradiol production.
Zhang Y1, Cao H2, Yu Z1, Peng HY1, Zhang CJ1.
Author information
Abstract

Background: Endometriosis is a complex estrogen-dependent disease that is defined as the presence of endometrial gland and stroma outside the uterine cavity. Although the exact mechanism for the development of endometriosis remains unclear, there is a large body of research data and circumstantial evidence that suggests a crucial role of estrogen in the establishment and maintenance of this disease. Objective: This study is an attempt to assess the effect of curcumin on inhibiting endometriosis endometrial cells and to investigate whether such an effect is mediated by reducing estradiol production. Materials and Methods: Endometriotic stromal cells, normal endometrial stromal cells, endometriotic epithelial cells and normal endometrial epithelial cells were isolated and cultured. E2 value of cells and the effect of curcumin on cell proliferation were evaluated. Finally, effect of curcumin on E2 assay was detected. Results: Electrochemiluminescence immunoassay results showed that E2 value of endometriotic epithelial cells was higher than the endometriotic stromal cells (p=0.037), while the expression of E2 in normal endometrial stromal and epithelial cells was extremely low. WST-8 result showed, compared with endometrial stromal cells, ectopic endometriotic stromal cells had a higher growth rate. After intervene with curcumin (10μmol/L, 30μmol/L and 50μmol/L) for 0-96h, the number of endometriotic stromal cells was reduced and cells growth slowed, compared with 0μmol/L group. Compared with 0μmol/L group, E2 level was lower after treatment with curcumin, especially in 30μmol/L and 50μmol/L group. Conclusion: In summary, in this study we found that E2 is important in ectopic endometrium, and epithelial cell is in dominant position with E2 secretion. Curcumin was able to suppress the proliferation of endometrial cells by reducing the E2 value.


http://www.ncbi.nlm.nih.gov/pubmed/24639774
Avatar de Usuario
Fisio
Administrador del Sitio
 
Mensajes: 6242
Registrado: Dom, 01 Sep 2013, 14:18

Re: Los niveles de bisfenol A en orina relacionados con el sobrepeso

Notapor Cobayahumana » Jue, 03 Abr 2014, 12:29

Yo esque la curcuma y tal no me gusta en la comida, estoy pensando en pillarme cápsulas vacias y meterle dentro un coctel bueno de micronutrientes y especias y tomarlas en cada comida.

Tu que combinación pondrias Fisio?
El mejor traje que puedes llevar es la desnudez.

https://www.facebook.com/ManuCulturismoAmateur
Avatar de Usuario
Cobayahumana
 
Mensajes: 516
Registrado: Lun, 30 Sep 2013, 22:05


Volver a Muscleblog

¿Quién está conectado?

Usuarios navegando por este Foro: Fisio y 6 invitados