Una sola dosis de vitamina D revierte la diabetes gestacional

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Una sola dosis de vitamina D revierte la diabetes gestacional

Notapor Fisio » Lun, 07 Abr 2014, 02:24

Una sola dosis de vitamina D revierte la diabetes gestacional. Lo siento por los antivitaminas :oops:

Effects of a single post-partum injection of a high dose of vitamin D on glucose tolerance and insulin resistance in mothers with first-time gestational diabetes mellitus.

This study was performed to determine the effect of a single, large, intramuscular injection of vitamin D post-partum on glucose tolerance and insulin resistance in women with gestational diabetes.
METHODS:

Forty-five participants in a randomized controlled trial on gestational diabetes mellitus were divided into an intervention group and a control group. Only subjects in the intervention group received one intramuscular injection of 300,000 IU of vitamin D3. HbA(1c), serum 25-hydroxyvitamin D3, fasting insulin and blood glucose, C-peptide, homeostasis model assessment insulin resistance index (HOMA-IR), β-cell function, insulin sensitivity and the Quantitative Insulin Sensitivity Check Index (QUICKI) were measured at baseline and after 3 months of intervention.
RESULTS:

Approximately 80% of the mothers had a degree of vitamin D deficiency. Post-intervention, this was found in 4.2 and 71.4% in the intervention and control groups, respectively. The medians of HOMA-IR indices before and after intervention were 0.6 and 0.5 (P = 0.7), respectively, in subjects in the intervention group, and 0.5 and 0.9 (P = 0.01) in subjects in the control group. The mean of the QUICKI fell only in the control group (P = 0.008). In the control group, β-cell function increased by ~8% (P = 0.01) and insulin sensitivity decreased after 3 months (P = 0.002). Post-intervention, the median C-peptide decreased in the intervention group and increased in the control group, but the change was significant only in the control group (P = 0.03).
CONCLUSIONS:

A single injection of 300,000 IU of vitamin D3 achieves a 3-month serum 25-hydroxyvitamin D range of 50-80 nmol/l and is an efficient, effective and safe procedure for improving the vitamin status and indices of insulin resistance in mothers with gestational diabetes after delivery.


http://www.ncbi.nlm.nih.gov/pubmed/21977923
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Re: Una sola dosis de vitamina D revierte la diabetes gestacional

Notapor Icok » Lun, 07 Abr 2014, 16:34

Bueno si es efectivo y seguro, lo veo genial.
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Re: Una sola dosis de vitamina D revierte la diabetes gestacional

Notapor Ango » Jue, 17 Abr 2014, 00:45

Mi cuñada vive en NY y cuando estaba embarazada el medico que la atendía la suplementaba con vit D y calcio durante todo el embarazo. Me extraño porque a mi mujer aquí en España no le dijeron nada de suplemento de vit D. Por lo que se ve también le dijeron que protegía de la pre eclampsia, que curiosamente tuvo mi mujer aunque todo salió bien.
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