La hipercolesterolemia familiar protege contra la diabetes

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La hipercolesterolemia familiar protege contra la diabetes

Notapor Fisio » Jue, 25 Jun 2015, 22:28

Genetic high cholesterol 'may help protect against type 2 diabetes'

Wed, 11 Mar 2015 14:33:00 EST

"High cholesterol LOWERS the risk of diabetes," is the Daily Mail's rather misleading headline, going on to say that, "New study reveals why taking statins may be harmful".

But this study looked at familial hypercholesterolemia (FH) and not at the more common form of high cholesterol, which is associated with a high-fat diet.

FH is caused by an abnormal gene that affects how much cholesterol is absorbed by cells (cholesterol uptake). People with FH usually require lifelong statin treatments. Statins are drugs that help reduce cholesterol levels, which can reduce the risk of serious complications of the condition, such as a heart attack.

As greater cholesterol uptake by cells has been linked to increased type 2 diabetes risk, the researchers expected that diabetes may be less common in people with FH.

The researchers studied 60,000 relatives of people with FH who were having a DNA test to see if they also had the condition. They compared how common type 2 diabetes was in those found to have the condition and those who were unaffected.

Overall, they found diabetes was slightly less common in those diagnosed with FH (1.75%) compared with those who did not have the condition (2.93%).

These findings certainly do not suggest that high cholesterol is good for you and taking statins is bad. Statins could potentially be lifesaving – without treatment, high circulating cholesterol levels could put people at a very high risk of heart attacks or strokes.


http://www.ncbi.nlm.nih.gov/pubmedhealt ... -diabetes/



Me encanta lo de que las estatinas son "potencialmente" efectivas. Jajajaja.
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